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HIV2 window period

I tested negative for HIV1/2 after 6 months post exposure with 3rd generation rapid test. I based in West Africa where HIV2 is prevalent. Is 6months negative test conclusive for HIV2.

  1. Hi . Your question is certainly understandable. Standard (including 3rd generation) HIV tests will pick up both HIV-1 and HIV-2 strains. This article discusses the types of tests: https://h-i-v.net/test-types and this one HIV-2: https://h-i-v.net/clinical/hiv-2-strain. They, however, won't differentiate between the two types of HIV. For that a differentiating assay may be needed. This article discusses the steps: https://www.michigan.gov/-/media/Project/Websites/mdhhs/Folder3/Folder8/Folder2/Folder108/Folder1/Folder208/Michigan_HIVTesting_Algorithm.pdf?rev=fb8005a7ed2f47408ce5b0b9eb96c5ce. Thus a negative 3rd generation test is negative for both HIV-1 and HIV-2. Hope this information is helpful. Best, Richard (Team Member)

    1. Thanks for your response. I understand 3rd generation rapid test can detect both subtypes accurately. But my concern is if 6 months negative result can conclusively rule out HIV2 infection. I have read in other forum,some conflicting information suggesting hiv2 antibodies takes longer time to develop to detectable amount than HIV1.
      I have been having weird symptoms since 3 Weeks post exposure without solution.

      1. Hi . Your concern about the window for HIV-2 testing is understandable given that it is known to progress more slowly. I have not found any indication that the seroconversion and detectability of hiv-2 is any slower. That said, we are not medical professional and, for your safety, cannot give medical advice over the internet. You may want to check with a medical professional, particularly, someone with knowledge of HIV. I wish I could offer you something more conclusive than the fact that none of the medical sources I located discussed a different testing period. Best, Richard (Team Member)

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